Marker-Assisted Selection to Increase Effective Population Size by Reducing Mendelian Segregation Variance
نویسندگان
چکیده
منابع مشابه
Marker-assisted selection to increase effective population size by reducing Mendelian segregation variance.
Using both the genetic drift and inbreeding approaches, we derive more general equations for effective size (N(e)) of a diploid species under random mating. These equations show explicitly that inbreeding or genetic drift comes from two sources, the variation in the number of offspring from each parent and the variation in contribution between these parents' own paternally and maternally derive...
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An approach to the optimal utilization of marker and pedigree information in minimizing the rates of inbreeding and genetic drift at the average locus of the genome (not just the marked loci) in a small diploid population is proposed, and its efficiency is investigated by stochastic simulations. The approach is based on estimating the expected pedigree of each chromosome by using marker and ind...
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Identifying the complete-linked molecular markers with target gene and mapping its chromosome locus is an important goal in plant breeding for gene cloning and marker-aided selection. Due to complexity of the interactions, in most of the agronomic traits, especially the interaction between the grain yield and the environmental factors, classic methods do not function appropriately in improving ...
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The efficiency of marker-assisted selection (MAS) based on an index incorporating both phenotypic and molecular information is evaluated with an analytical approach that takes into account the size of the experiment. We consider the case of a population derived from a cross between two homozygous lines, which is commonly used in plant breeding, and we study the relative efficiency of MAS compar...
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A deterministic two-loci model was developed to predict genetic response to marker-assisted selection (MAS) in one generation and in multiple generations. Formulas were derived to relate linkage disequilibrium in a population to the proportion of additive genetic variance used by MAS, and in turn to an extra improvement in genetic response over phenotypic selection. Predictions of the response ...
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ژورنال
عنوان ژورنال: Genetics
سال: 2000
ISSN: 1943-2631
DOI: 10.1093/genetics/154.1.475